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Olpha has a comprehensive expertise in active pharmaceutical ingredient manufacturing and intermediates

APIs — Drug Substances

Amantadine hydrochloride
USP; CEP
Therapeutic Categories
Antiviral (Influenza A);  Antiparkinsonian;
Pharmacopoeia
Ph. Eur. (CEP), USP
CAS No.
[ 665–66–7 ]
Stage
C - Commercial
Chlorobutanol hemihydrate
CEP
Therapeutic Categories
Analgesic (dental)  sedative-hypnotic  preservative
Pharmacopoeia
Ph. Eur. (CEP)
CAS No.
[ 6001-64-5 ]
Stage
C - Commercial
Furazidin (Furagin®)
ASMF available
Therapeutic Categories
Antimicrobals
CAS No.
[ 1672-88-4 ]
Stage
C - Commercial
Meldonium dihydrate
Therapeutic Categories
Cardiac health
Pharmacopoeia
In-house
CAS No.
[ 86426-17-7 ]
Stage
C - Commercial
Memantine hydrochloride
USP, In-house
Therapeutic Categories
Anti-Dementia drug
Pharmacopoeia
USP, In-house
CAS No.
[ 41100-52-1 ]
Stage
C - Commercial
Nitrofurantoin Macrocrystalline
USP
Therapeutic Categories
Antibacterial
Pharmacopoeia
USP
CAS No.
[ 67-20-9 ]
Stage
P - Pilot
Nitrofurantoin monohydrate
Ph.Eur
Therapeutic Categories
Antibacterial
CAS No.
[ 17140-81-7 ]
Stage
C - Commercial
Phenazepam
ASMF available
Therapeutic Categories
Tranquillisers
CAS No.
[ 51753-57-2 ]
Stage
C - Commercial
Rimantadine hydrochloride
USP
Therapeutic Categories
Antiviral
Pharmacopoeia
USP
CAS No.
[ 1501-84-4 ]
Stage
C - Commercial
Vildagliptin
ASMF available
Therapeutic Categories
Antidiabetic
CAS No.
[ 274901-16-5 ]
Stage
C - Commercial

Intermediates

5-Hydroxy-2-adamantanone
Molecular Formula
C₁₀H₁₄O₂
CAS No.
[ 20098-14-0 ]
Stage
L – Laboratory
3-Hydroxymethyl-1-adamantanol
Molecular Formula
C₁₁H₁₈O₂
CAS No.
[ 38584-37-1 ]
Stage
L – Laboratory
1-Adamantyl methyl ketone (1-Acetyladamantane)
1-Acetyladamantane
Molecular Formula
C₁₂H₁₈O
Key Use
Rimantadine hydrochloride
CAS No.
[ 1660-04-4 ]
Stage
C - Commercial
2-Adamantanone
Molecular Formula
C₁₀H₁₄O
CAS No.
[ 700-58-3 ]
Stage
C - Commercial
2-Adamantanol
(2-Hydroxyladamantane)
Molecular Formula
C₁₀H₁₆O
CAS No.
[ 700-57-2 ]
Stage
P - Pilot
1,3-Dimethyladamantane
Molecular Formula
C₁₂H₂₀O
Key Use
Memantine hydrochloride
CAS No.
[ 702-79-4 ]
Stage
C - Commercial
2-Aminoadamantane hydrochloride
Molecular Formula
C₁₀H₁₇N·HCl
CAS No.
[ 10523-68-9 ]
Stage
P - Pilot
3-Amino-1-hydroxy-adamantane
Molecular Formula
C₁₀H₁₇NO
Key Use
Vildagliptin
CAS No.
[ 702-82-9 ]
Stage
C - Commercial
1-Acetylamidoadamantane
Molecular Formula
C₁₂H₁₉NO
CAS No.
[ 880-52-4 ]
Stage
L – Laboratory
1-Chloro-3,5-dimethyladamantane
Molecular Formula
C₁₂H₁₉Cl
Key Use
Memantine hydrochloride
CAS No.
[ 707-36-8 ]
Stage
C - Commercial
1-Hydroxy-3,5-dimethyladamantane
Molecular Formula
C₁₂H₂₀O
Key Use
Memantine hydrochloride
CAS No.
[ 707-37-9 ]
Stage
C - Commercial
1,3-Dihydroxyadamantane
1,3-Adamantanediol
Molecular Formula
C₁₀H₁₆O₂
CAS No.
[ 5001-18-3 ]
Stage
L – Laboratory
1-Adamantaneacetic acid
1-Adamantylacetic acid
Molecular Formula
C₁₂H₁₈O₂
CAS No.
[ 4942-47-6 ]
Stage
P - Pilot
1-Adamantanemethanol
1-Adamantylmethanol
Molecular Formula
C₁₁H₁₈O
Key Use
Rimantadine hydrochloride
CAS No.
[ 770-71-8 ]
Stage
P - Pilot
1-Adamantaneethanol
2-(1-Adamantylethanol)
Molecular Formula
C₁₂H₂₀O
CAS No.
[ 6240-11-5 ]
Stage
P - Pilot
1-Acetylamido-3,5-dimethyladamantane
Molecular Formula
C₁₄H₂₃NO
Key Use
Memantine hydrochloride
CAS No.
[ 19982-07-1 ]
Stage
L – Laboratory
Dimethyl-5-hydroxy-1,3-Adamantane dicarboxylate
Molecular Formula
C₁₄H₂₀O₅
CAS No.
[ 213274-64-7 ]
Stage
P - Pilot
3-Quinuclidinone hydrochloride
Molecular Formula
C₇H₁₁NO HCl
Key Use
Cevimeline, Aclidinium
CAS No.
[ 1193-65-3 ]
Stage
C - Commercial
3-Carbethoxyquinuclidine
Molecular Formula
C₁₀H₁₇NO₂
Key Use
Quifenadine
CAS No.
[ 6238–33–1 ]
Stage
C - Commercial
3-Quinuclidinol
Molecular Formula
C₇H₁₃NO
Key Use
Aceclidine, Aclidinium
CAS No.
[ 1619–34–7 ]
Stage
C - Commercial
S–(+)–3–Quinuclidinol
ee 99.5%
Molecular Formula
C₇H₁₃NO
CAS No.
[ 34583–34–1 ]
Stage
P - Pilot
R–(–)–3–Quinuclidinol
ee 99.9%
Molecular Formula
C₇H₁₃NO
Key Use
Aclidinium, Solifenacin
CAS No.
[ 25333–42–0 ]
Stage
C - Commercial
3–Aminoquinuclidine dihydrochloride
Molecular Formula
C₇H₁₄N₂ ₂HCl
CAS No.
[ 6530–09–2 ]
Stage
C - Commercial
R–(+)–3–Aminoquinuclidine dihydrochloride
up to 99.5%
Molecular Formula
C₇H₁₄N₂ ₂HCl
CAS No.
[ 123536–14–1 ]
Stage
P - Pilot
S–(–)–3–Aminoquinuclidine dihydrochloride
up to 99.5%
Molecular Formula
C₇H₁₄N₂ ₂HCl
Key Use
Palonosetron
CAS No.
[ 119904–90–4 ]
Stage
C - Commercial
R-3-hydroxymethyl quinuclidine hydrochloride
Free base
Molecular Formula
C₈H₁₅NO HCl
CAS No.
[ 138874-55-2 ]
Stage
L – Laboratory
S-3-hydroxymethyl quinuclidine hydrochloride
Free base
Molecular Formula
C₈H₁₅NO HCl
CAS No.
[ 88644-21-7 ]
Stage
L – Laboratory
3-aminomethyl-quinuclidine dihydrochloride
Molecular Formula
C₈H₁₆N₂ ₂HCI
Key Use
[ 865887-14-5 ]
CAS No.
[ 1501-84-4 ]
Stage
L – Laboratory
R-3-aminomethyl-quinuclidine dihydrochloride
Molecular Formula
C₈H₁₆N₂ ₂HCI
Stage
L – Laboratory
R-3-aminomethyl-quinuclidine dihydrochloride
Molecular Formula
C₈H₁₆N₂ ₂HCI
Stage
L – Laboratory

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